77 Results for "

Prunus pseudocerasus (Lindl.) G. Don

" in MedChemExpress (MCE) Product Catalog:
Products (77)

77 Results for "Prunus pseudocerasus (Lindl.) G. Don" in MCE Product Catalog:

17
17 Publications Verification
Cat. No.: HY-108357
CAS No.: 157-03-9
Purity:  99.98%
Synonyms: L-6-Diazo-5-oxonorleucine; Don
6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine; DON) is a glutamine antagonist that irreversibly inhibits the catabolic effect of glutamine. 6-Diazo-5-oxo-L-nor-Leucine shows good anticancer activity (especially in pancreatic cancer) and reduces the self-renewal potential and metastatic capacity of tumour cells. 6-Diazo-5-oxo-L-nor-Leucine also possesses antibacterial and antiviral activity .
loading...
    loading...
9
9 Cited Publications
Cat. No.: HY-122218
CAS No.: 1998725-11-3
Purity:  ≥98.0%
Target:  

Glutaminase

Research Areas:  

Neurological Disease

JHU-083, a proagent of 6-diazo-5-oxo-L-norleucine (DON; HY-108357), is an orally active and selective glutaminase antagonist. JHU-083 blocks glutaminase activity in brain CD11b + cells and experimental cerebral malaria (ECM) resulting in a net decrease of glutamate levels in the animals .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-N1547
CAS No.: 3443-28-5
Prudomestin, isolated from the heartwood of Prunus domestica, shows potent xanthine oxidase (XO) inhibitory activity (IC50≈6 µM) .
loading...
    loading...
Cat. No.: HY-N11678
CAS No.: 131180-21-7
Synonyms: Don-3-β-D-glucoside; Deoxynivalenol 3-glucoside
Target:  

Drug Metabolite

Deoxynivalenol-3-β-D-glucoside (DON-3-β-D-glucoside) is a plant metabolite of the Fusarium mycotoxin Deoxynivalenol (HY-N6684). Deoxynivalenol-3-β-D-glucoside exhibits lower toxicity than Deoxynivalenol in vitro and in vivo .
loading...
    loading...
Cat. No.: HY-W099547
CAS No.: 2197-63-9
Dihexadecyl hydrogen phosphateIt is an organic compound belonging to phospholipids. It's often used as an emulsifier, which means it helps mix two substances together that don't usually mix well, such as oil and water. Dihexadecyl hydrogen phosphateIt has several applications in the food industry, especially in the production of processed foods where it improves texture and stability. Additionally, it has applications in the pharmaceutical industry where it can be used ain the generation of micelles, liposomes, and other types of artificial membranes.
loading...
    loading...
Cat. No.: HY-N8903
CAS No.: 222973-44-6
Mumefural is a bioactive component of the processed fruit of Prunus mume Sieb. Mumefural inhibits platelet aggregation. Mumefural shows anti-thrombotic effects and ameliorates cognitive impairment .
loading...
    loading...
Cat. No.: HY-P991023
CAS No.: 2911590-72-0
Synonyms: 6MW3211

Target:  

CD47 PD-1/PD-L1

Research Areas:  

Cancer

Safimestomig (6MW3211) is an CD47/PD-L1-targeting bispecific antibody. Safimestomig blocks CD47-mediated 'don't eat me' signaling and selectively binds to CD47 on tumor cells. Safimestomig blocks PD-L1-mediated immune checkpoint signaling. Safimestomig can be used for the research of cancer .
loading...
    loading...
Cat. No.: HY-N6005
CAS No.: 3843-74-1
Methyl caffeate is a phenylpropanoid, antibacterial agent, and Apoptosis-inducing agent. Methyl caffeate can be isolated from the flowers of peach Prunus persica (L.). Methyl caffeate upregulates the expression of pro-apoptotic proteins Bid, Bax and p53, and downregulates the expression of anti-apoptotic protein BCL-2. Methyl caffeate downregulates SASP factors. Methyl caffeate enhances glucose-stimulated insulin secretion. Methyl caffeate inhibits the growth of Gram-positive bacteria, Gram-negative bacteria, fungi, and Mycobacterium tuberculosis strains. Methyl caffeate can be used in studies related to breast cancer, type 2 diabetes, and tuberculosis .
loading...
    loading...
Cat. No.: HY-D0854
CAS No.: 3244-88-0
Synonyms: Acid Violet 19; Acid fuchsin sodium
Acid Red is a class of synthetic dyes commonly used in the textile, paper and ink industries. They are in the category of acid dyes, which means they are water soluble and have acidic properties. Acid Red dye produces bright, vibrant colors that don't fade easily, but are not as durable as some other dyes. They can be used to dye a wide variety of fibers including wool, silk and nylon, as well as paper and leather.
loading...
    loading...
Cat. No.: HY-N7683
CAS No.: 89595-66-4
Prunetin 5-O-β-D-glucopyranoside is an isoflavone. Prunetin 5-O-β-D-glucopyranoside can be isolated from the pedicels of Prunus avium and Prunus cerasus. Prunetin 5-O-β-D-glucopyranoside acts as a non-competitive α-glucosidase inhibitor, with a IC50 of 56.05 μg/mL and a Ki of 121 μg/mL against Saccharomyces cerevisiae α-glucosidase. Prunetin 5-O-β-D-glucopyranoside can be used in studies related to type 2 diabetes .
loading...
    loading...
Cat. No.: HY-N3706
CAS No.: 15297-92-4
Target:  

Fungal

Dehydro-α-lapachone can be isolated from the methanol extract of stems of Catalpa ovata G Don. Dehydro-α-lapachone inhibits mycelial growth of Botrytis cinerea with IC50 value 0.41 mg/L .
loading...
    loading...
Cat. No.: HY-P11097
CAS No.: 3056822-31-9
Target:  

CD47

Research Areas:  

Cardiovascular Disease Cancer

Pep-20 is a CD47 binder with a human Kd of 2.91 µM and a murine Kd of 3.63 µM. Pep-20 blocks the interaction between CD47 and SIRPα, with an IC50 of 24.56 µM for human targets and 12.03 µM for murine targets. Pep-20 also acts as a phagocytosis enhancer and an inducer of anti-tumor immune responses. By blocking the CD47/SIRPα interaction, Pep-20 reduces the tyrosine phosphorylation level of SIRPα, disrupts the inhibitory "don't eat me" signaling pathway, enhances macrophage-mediated phagocytosis of solid tumor cells and hematologic tumor cells, and promotes macrophage mobilization of anti-tumor T-cell responses. Pep-20 can be used in research related to solid tumors, hematologic malignancies, breast cancer, and pancreatic cancer .
loading...
    loading...
Cat. No.: HY-N4276
CAS No.: 33464-78-7
Nortracheloside is a lignan isolated from Trachelospermum jasminoides (Lindl.) Lem .
loading...
    loading...
Cat. No.: HY-N9106
CAS No.: 200127-80-6
3′-Methoxydaidzin is a flavonoid compound isolated from the leaves of Ilex cornuta Lindl ex Paxt .
loading...
    loading...
Cat. No.: HY-N6685
CAS No.: 50722-38-8
Synonyms: 3-AcDon; 3-ADon
3-Acetyldeoxynivalenol (3-AcDON; 3ADON), a trichothecene mycotoxin deoxynivalenol (DON) acetylated derivative, is a brain-penetrant Fusarium mycotoxin. 3-Acetyldeoxynivalenol induces mRNA expression and production of inflammatory chemokine IL-8 in intestinal cells .
loading...
    loading...
Cat. No.: HY-N1216
CAS No.: 126882-53-9
Ssioriside (compound 9) is a lignan xyloside, which can be isolated from the barks of Prunus ssiori and Prunus padus .
loading...
    loading...
Cat. No.: HY-179120
CAS No.: 3095661-21-2
Target:  

Myosin

Research Areas:  

Infection

ZJS178 is a novel inhibitor of myosin I. ZJS178 is a fungicide that has inhibitory activity against Fusarium graminearum and can reduce DON toxin synthesis. ZJS178 can be used for research on plant diseases such as wheat scab .
loading...
    loading...
Cat. No.: HY-178717
CAS No.: 3057478-36-8
Target:  

Fungal

Research Areas:  

Infection

WML-01 is a fungicide with EC50s of 0.079, 0.72 and 2.02 μg/mL against F. graminearum, F. fujikuroi and S. sclerotiorum. WML-01 disrupts the cell membrane of F. graminearum and induces deposition of lipid droplets. WML-01 inhibits Deoxynivalenol (DON) (HY-N6684) biosynthesis with no cross-resistance and strongly suppresses ribosomal subunit assembly, impairing protein synthesis. WML-01 effectively controls the fusarium head blight (FHB) epidemic .
loading...
    loading...
Cat. No.: HY-N20024
Synonyms: Prunus pseudocerasus extract
Category:  

Extract

Target:  

Others

Cherry extract (Prunus pseudocerasus extract) is an extract of cherry (Prunus avium) with antioxidant and anti-inflammatory properties.
loading...
    loading...
Cat. No.: HY-108357R
CAS No.: 157-03-9
Synonyms: L-6-Diazo-5-oxonorleucine (Standard); Don (Standard)
6-Diazo-5-oxo-L-nor-Leucine (Standard) is the analytical standard of 6-Diazo-5-oxo-L-nor-Leucine. This product is intended for research and analytical applications. 6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine; DON) is a glutamine antagonist that irreversibly inhibits the catabolic effect of glutamine. 6-Diazo-5-oxo-L-nor-Leucine shows good anticancer activity (especially in pancreatic cancer) and reduces the self-renewal potential and metastatic capacity of tumour cells. 6-Diazo-5-oxo-L-nor-Leucine also possesses antibacterial and antiviral activity[1][2][3].
loading...
    loading...